The Avezzano railway station is located in Piazza Matteotti. It was built in 1888 and destroyed by the 1915 Avezzano earthquake. Rebuilt in 1945, after World War II, it is the main railway station in Marsica, along the railroads Rome-Sulmona–Pescara and Avezzano-Roccasecca.
The bus station is located in Piazzale J.F. Kennedy, behind the railway station.